RPN1-ALDOA Fusion FISH Probe
The RPN1-ALDOA Fusion FISH Probe is used to confirm a fusion of the RPN1 and ALDOA genes. The fusion of the RPN1 and ALDOA genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPN1-ALDOA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-RERE | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-REOR | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-REGO | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-REGR | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-REAQ | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-ORRE | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-OROR | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-ORGO | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-GORE | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-GOOR | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-GOGO | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-GOGR | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-GRRE | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-GROR | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-GRGO | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-GRGR | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-AQRE | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-AQOR | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-AQGO | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-AQGR | 20 (40 μL) | 200 μL |
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| RPN1-ALDOA-20-AQAQ | 20 (40 μL) | 200 μL |
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ALDOA Gene Summary
This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]
Gene Name: Aldolase, Fructose-bisphosphate A
Chromosome: CHR16: 30064410 -30081741
Locus: 16p11.2
RPN1 Gene Summary
This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. [provided by RefSeq, Jul 2008]
Gene Name: Ribophorin I
Chromosome: CHR3: 128338812 -128369719
Locus: 3q21.3
Gene Diseases
The RPN1 ALDOA Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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