RPLP2-TALDO1 Fusion FISH Probe
The RPLP2-TALDO1 Fusion FISH Probe is used to confirm a fusion of the RPLP2 and TALDO1 genes. The fusion of the RPLP2 and TALDO1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPLP2-TALDO1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-RERE | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-REOR | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-REGO | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-REGR | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-REAQ | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-ORRE | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-OROR | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-ORGO | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-GORE | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-GOOR | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-GOGO | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-GOGR | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-GRRE | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-GROR | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-GRGO | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-GRGR | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-AQRE | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-AQOR | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-AQGO | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-AQGR | 20 (40 μL) | 200 μL |
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| RPLP2-TALDO1-20-AQAQ | 20 (40 μL) | 200 μL |
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RPLP2 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Name: Ribosomal Protein Lateral Stalk Subunit P2
Chromosome: CHR11: 809935 -812876
Locus: 11p15.5
TALDO1 Gene Summary
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]
Gene Name: Transaldolase 1
Chromosome: CHR11: 747431 -765024
Locus: 11p15.5
Gene Diseases
The RPLP2 TALDO1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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