RPLP2-ACPP Fusion FISH Probe
The RPLP2-ACPP Fusion FISH Probe is used to confirm a fusion of the RPLP2 and ACPP genes. The fusion of the RPLP2 and ACPP genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RPLP2-ACPP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-RERE | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-REOR | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-REGO | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-REGR | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-OROR | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-GORE | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-GROR | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| RPLP2-ACPP-20-AQAQ | 20 (40 μL) | 200 μL |
|
ACPP Gene Summary
This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]
Gene Name: Acid Phosphatase, Prostate
Chromosome: CHR3: 132036210 -132087146
Locus: 3q22.1
RPLP2 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Name: Ribosomal Protein Lateral Stalk Subunit P2
Chromosome: CHR11: 809935 -812876
Locus: 11p15.5
Gene Diseases
The RPLP2 ACPP Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|