RPLP1-TMEFF2 Fusion FISH Probe
The RPLP1-TMEFF2 Fusion FISH Probe is used to confirm a fusion of the RPLP1 and TMEFF2 genes. The fusion of the RPLP1 and TMEFF2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPLP1-TMEFF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-RERE | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-REOR | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-REGO | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-REGR | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-REAQ | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-ORRE | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-OROR | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-ORGO | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-GORE | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-GOOR | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-GOGO | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-GOGR | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-GRRE | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-GROR | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-GRGO | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-GRGR | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-AQRE | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-AQOR | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-AQGO | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-AQGR | 20 (40 μL) | 200 μL |
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| RPLP1-TMEFF2-20-AQAQ | 20 (40 μL) | 200 μL |
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RPLP1 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P2. The P1 protein can interact with P0 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Two alternatively spliced transcript variants that encode different proteins have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Name: Ribosomal Protein Lateral Stalk Subunit P1
Chromosome: CHR15: 69745158 -69747884
Locus: 15q23
TMEFF2 Gene Summary
This gene encodes a member of the tomoregulin family of transmembrane proteins. This protein has been shown to function as both an oncogene and a tumor suppressor depending on the cellular context and may regulate prostate cancer cell invasion. Multiple soluble forms of this protein have been identified that arise from both an alternative splice variant and ectodomain shedding. Additionally, this gene has been found to be hypermethylated in multiple cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Gene Name: Transmembrane Protein With EGF Like And Two Follistatin Like Domains 2
Chromosome: CHR2: 192814746 -193059644
Locus: 2q32.3
Gene Diseases
The RPLP1 TMEFF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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