RPL37A-NDUFV1 Fusion FISH Probe
The RPL37A-NDUFV1 Fusion FISH Probe is used to confirm a fusion of the RPL37A and NDUFV1 genes. The fusion of the RPL37A and NDUFV1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPL37A-NDUFV1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-RERE | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-REOR | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-REGO | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-REGR | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-REAQ | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-ORRE | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-OROR | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-ORGO | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-GORE | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-GOOR | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-GOGO | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-GOGR | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-GRRE | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-GROR | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-GRGO | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-GRGR | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-AQRE | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-AQOR | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-AQGO | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-AQGR | 20 (40 μL) | 200 μL |
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| RPL37A-NDUFV1-20-AQAQ | 20 (40 μL) | 200 μL |
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NDUFV1 Gene Summary
The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]
Gene Name: NADH:ubiquinone Oxidoreductase Core Subunit V1
Chromosome: CHR11: 67374322 -67380012
Locus: 11q13.2
RPL37A Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37AE family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C4-type zinc finger-like domain. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Name: Ribosomal Protein L37a
Chromosome: CHR2: 217363519 -217366188
Locus: 2q35
Gene Diseases
The RPL37A NDUFV1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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