RPL19-CCL11 Fusion FISH Probe
The RPL19-CCL11 Fusion FISH Probe is used to confirm a fusion of the RPL19 and CCL11 genes. The fusion of the RPL19 and CCL11 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPL19-CCL11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-RERE | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-REOR | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-REGO | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-REGR | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-REAQ | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-ORRE | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-OROR | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-ORGO | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-GORE | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-GOOR | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-GOGO | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-GOGR | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-GRRE | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-GROR | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-GRGO | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-GRGR | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-AQRE | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-AQOR | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-AQGO | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-AQGR | 20 (40 μL) | 200 μL |
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| RPL19-CCL11-20-AQAQ | 20 (40 μL) | 200 μL |
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RPL19 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L19E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Name: Ribosomal Protein L19
Chromosome: CHR17: 37356535 -37360980
Locus: 17q12
CCL11 Gene Summary
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
Gene Name: C-C Motif Chemokine Ligand 11
Chromosome: CHR17: 32612686 -32615199
Locus: 17q12
Gene Diseases
The RPL19 CCL11 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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