RPL19-CACNB1 Fusion FISH Probe
The RPL19-CACNB1 Fusion FISH Probe is used to confirm a fusion of the RPL19 and CACNB1 genes. The fusion of the RPL19 and CACNB1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPL19-CACNB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-RERE | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-REOR | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-REGO | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-REGR | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-REAQ | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-ORRE | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-OROR | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-ORGO | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-GORE | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-GOOR | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-GOGO | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-GOGR | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-GRRE | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-GROR | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-GRGO | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-GRGR | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-AQRE | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-AQOR | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-AQGO | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-AQGR | 20 (40 μL) | 200 μL |
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| RPL19-CACNB1-20-AQAQ | 20 (40 μL) | 200 μL |
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CACNB1 Gene Summary
The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Calcium Voltage-gated Channel Auxiliary Subunit Beta 1
Chromosome: CHR17: 37329708 -37353901
Locus: 17q12
RPL19 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L19E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Name: Ribosomal Protein L19
Chromosome: CHR17: 37356535 -37360980
Locus: 17q12
Gene Diseases
The RPL19 CACNB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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