RPL18-SQSTM1 Fusion FISH Probe
The RPL18-SQSTM1 Fusion FISH Probe is used to confirm a fusion of the RPL18 and SQSTM1 genes. The fusion of the RPL18 and SQSTM1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RPL18-SQSTM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| RPL18-SQSTM1-20-AQAQ | 20 (40 μL) | 200 μL |
|
RPL18 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18E family of ribosomal proteins that is a component of the 60S subunit. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Name: Ribosomal Protein L18
Chromosome: CHR19: 49118587 -49122433
Locus: 19q13.33
SQSTM1 Gene Summary
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]
Gene Name: Sequestosome 1
Chromosome: CHR5: 179233387 -179265077
Locus: 5q35.3
Gene Diseases
The RPL18 SQSTM1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|