RPL18-ABCF1 Fusion FISH Probe
The RPL18-ABCF1 Fusion FISH Probe is used to confirm a fusion of the RPL18 and ABCF1 genes. The fusion of the RPL18 and ABCF1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPL18-ABCF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-RERE | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-REOR | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-REGO | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-REGR | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-REAQ | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-ORRE | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-OROR | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-ORGO | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-GORE | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-GOOR | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-GOGO | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-GOGR | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-GRRE | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-GROR | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-GRGO | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-GRGR | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-AQRE | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-AQOR | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-AQGO | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-AQGR | 20 (40 μL) | 200 μL |
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| RPL18-ABCF1-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCF1 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily F Member 1
Chromosome: CHR6: 30539169 -30559309
Locus: 6p21.33
RPL18 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18E family of ribosomal proteins that is a component of the 60S subunit. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Name: Ribosomal Protein L18
Chromosome: CHR19: 49118587 -49122433
Locus: 19q13.33
Gene Diseases
The RPL18 ABCF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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