RPL11-SIAE Fusion FISH Probe
The RPL11-SIAE Fusion FISH Probe is used to confirm a fusion of the RPL11 and SIAE genes. The fusion of the RPL11 and SIAE genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPL11-SIAE-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-RERE | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-REOR | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-REGO | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-REGR | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-REAQ | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-ORRE | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-OROR | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-ORGO | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-GORE | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-GOOR | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-GOGO | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-GOGR | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-GRRE | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-GROR | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-GRGO | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-GRGR | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-AQRE | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-AQOR | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-AQGO | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-AQGR | 20 (40 μL) | 200 μL |
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| RPL11-SIAE-20-AQAQ | 20 (40 μL) | 200 μL |
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RPL11 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L5P family of ribosomal proteins. It is located in the cytoplasm. The protein probably associates with the 5S rRNA. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Dec 2010]
Gene Name: Ribosomal Protein L11
Chromosome: CHR1: 24018268 -24022915
Locus: 1p36.11
SIAE Gene Summary
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Name: Sialic Acid Acetylesterase
Chromosome: CHR11: 124505684 -124546199
Locus: 11q24.2
Gene Diseases
The RPL11 SIAE Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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