RPF1-PRKACB Fusion FISH Probe
The RPF1-PRKACB Fusion FISH Probe is used to confirm a fusion of the RPF1 and PRKACB genes. The fusion of the RPF1 and PRKACB genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPF1-PRKACB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-RERE | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-REOR | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-REGO | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-REGR | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-REAQ | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-ORRE | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-OROR | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-ORGO | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-GORE | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-GOOR | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-GOGO | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-GOGR | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-GRRE | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-GROR | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-GRGO | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-GRGR | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-AQRE | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-AQOR | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-AQGO | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-AQGR | 20 (40 μL) | 200 μL |
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| RPF1-PRKACB-20-AQAQ | 20 (40 μL) | 200 μL |
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PRKACB Gene Summary
The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2014]
Gene Name: Protein Kinase CAMP-activated Catalytic Subunit Beta
Chromosome: CHR1: 84543744 -84704181
Locus: 1p31.1
RPF1 Gene Summary
The Ribosome Production Factor 1 Homolog (RPF1) gene is located on chr1 :84944919-84964033 at 1p22.3.
Gene Name: Ribosome Production Factor 1 Homolog
Chromosome: CHR1: 84944919 -84964033
Locus: 1p22.3
Gene Diseases
The RPF1 PRKACB Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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