RPAP3-KRT74 Fusion FISH Probe
The RPAP3-KRT74 Fusion FISH Probe is used to confirm a fusion of the RPAP3 and KRT74 genes. The fusion of the RPAP3 and KRT74 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RPAP3-KRT74-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-RERE | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-REOR | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-REGO | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-REGR | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-REAQ | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-ORRE | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-OROR | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-ORGO | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-ORAQ | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-GORE | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-GOOR | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-GOGO | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-GOGR | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-GOAQ | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-GRRE | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-GROR | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-GRGO | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-GRGR | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-GRAQ | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-AQRE | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-AQOR | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-AQGO | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-AQGR | 20 (40 μL) | 200 μL |
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| RPAP3-KRT74-20-AQAQ | 20 (40 μL) | 200 μL |
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RPAP3 Gene Summary
This gene encodes an RNA polymerase II-associated protein. The encoded protein may function in transcriptional regulation and may also regulate apoptosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
Gene Name: RNA Polymerase II Associated Protein 3
Chromosome: CHR12: 48055714 -48099844
Locus: 12q13.11
KRT74 Gene Summary
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This protein belongs to a family of keratins that are specifically expressed in the inner root sheath of hair follicles.[provided by RefSeq, Jun 2009]
Gene Name: Keratin 74
Chromosome: CHR12: 52959602 -52967609
Locus: 12q13.13
Gene Diseases
The RPAP3 KRT74 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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