RORA-CLSTN2 Fusion FISH Probe
The RORA-CLSTN2 Fusion FISH Probe is used to confirm a fusion of the RORA and CLSTN2 genes. The fusion of the RORA and CLSTN2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RORA-CLSTN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-RERE | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-REOR | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-REGO | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-REGR | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-REAQ | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-ORRE | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-OROR | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-ORGO | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-GORE | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-GOOR | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-GOGO | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-GOGR | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-GRRE | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-GROR | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-GRGO | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-GRGR | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-AQRE | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-AQOR | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-AQGO | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-AQGR | 20 (40 μL) | 200 μL |
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| RORA-CLSTN2-20-AQAQ | 20 (40 μL) | 200 μL |
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RORA Gene Summary
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]
Gene Name: RAR Related Orphan Receptor A
Chromosome: CHR15: 60780482 -61521502
Locus: 15q22.2
CLSTN2 Gene Summary
The Calsyntenin 2 (CLSTN2) gene is located on chr3 :139654026-140286919 at 3q23.
Gene Name: Calsyntenin 2
Chromosome: CHR3: 139654026 -140286919
Locus: 3q23
Gene Diseases
The RORA CLSTN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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