ROCK1-FABP2 Fusion FISH Probe
The ROCK1-FABP2 Fusion FISH Probe is used to confirm a fusion of the ROCK1 and FABP2 genes. The fusion of the ROCK1 and FABP2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ROCK1-FABP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-RERE | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-REOR | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-REGO | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-REGR | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-REAQ | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-ORRE | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-OROR | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-ORGO | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-GORE | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-GOOR | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-GOGO | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-GOGR | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-GRRE | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-GROR | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-GRGO | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-GRGR | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-AQRE | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-AQOR | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-AQGO | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-AQGR | 20 (40 μL) | 200 μL |
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| ROCK1-FABP2-20-AQAQ | 20 (40 μL) | 200 μL |
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FABP2 Gene Summary
The protein encoded by this gene is an intracellular fatty acid-binding protein that participates in the uptake, intracellular metabolism, and transport of long-chain fatty acids. The encoded protein is also involved in the modulation of cell growth and proliferation. This protein binds saturated long-chain fatty acids with high affinity, and may act as a lipid sensor to maintain energy homeostasis. [provided by RefSeq, Aug 2017]
Gene Name: Fatty Acid Binding Protein 2
Chromosome: CHR4: 120238404 -120243316
Locus: 4q26
ROCK1 Gene Summary
This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015]
Gene Name: Rho Associated Coiled-coil Containing Protein Kinase 1
Chromosome: CHR18: 18529702 -18691812
Locus: 18q11.1
Gene Diseases
The ROCK1 FABP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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