ROBO1-HMCN1 Fusion FISH Probe
The ROBO1-HMCN1 Fusion FISH Probe is used to confirm a fusion of the ROBO1 and HMCN1 genes. The fusion of the ROBO1 and HMCN1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ROBO1-HMCN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-RERE | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-REOR | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-REGO | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-REGR | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-REAQ | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-ORRE | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-OROR | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-ORGO | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-GORE | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-GOOR | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-GOGO | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-GOGR | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-GRRE | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-GROR | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-GRGO | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-GRGR | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-AQRE | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-AQOR | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-AQGO | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-AQGR | 20 (40 μL) | 200 μL |
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| ROBO1-HMCN1-20-AQAQ | 20 (40 μL) | 200 μL |
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ROBO1 Gene Summary
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Gene Name: Roundabout Guidance Receptor 1
Chromosome: CHR3: 78646387 -79817059
Locus: 3p12.3
HMCN1 Gene Summary
This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]
Gene Name: Hemicentin 1
Chromosome: CHR1: 185703682 -186160085
Locus: 1q25.3-q31.1
Gene Diseases
The ROBO1 HMCN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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