RNH1-MYBPC1 Fusion FISH Probe
The RNH1-MYBPC1 Fusion FISH Probe is used to confirm a fusion of the RNH1 and MYBPC1 genes. The fusion of the RNH1 and MYBPC1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNH1-MYBPC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-RERE | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-REOR | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-REGO | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-REGR | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-REAQ | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-ORRE | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-OROR | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-ORGO | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-GORE | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-GOOR | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-GOGO | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-GOGR | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-GRRE | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-GROR | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-GRGO | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-GRGR | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-AQRE | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-AQOR | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-AQGO | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-AQGR | 20 (40 μL) | 200 μL |
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| RNH1-MYBPC1-20-AQAQ | 20 (40 μL) | 200 μL |
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MYBPC1 Gene Summary
This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Binding Protein C, Slow Type
Chromosome: CHR12: 101988746 -102079658
Locus: 12q23.2
RNH1 Gene Summary
Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010]
Gene Name: Ribonuclease/angiogenin Inhibitor 1
Chromosome: CHR11: 494511 -507273
Locus: 11p15.5
Gene Diseases
The RNH1 MYBPC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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