RNF44-NXF3 Fusion FISH Probe
The RNF44-NXF3 Fusion FISH Probe is used to confirm a fusion of the RNF44 and NXF3 genes. The fusion of the RNF44 and NXF3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNF44-NXF3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-RERE | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-REOR | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-REGO | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-REGR | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-REAQ | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-ORRE | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-OROR | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-ORGO | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-GORE | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-GOOR | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-GOGO | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-GOGR | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-GRRE | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-GROR | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-GRGO | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-GRGR | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-AQRE | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-AQOR | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-AQGO | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-AQGR | 20 (40 μL) | 200 μL |
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| RNF44-NXF3-20-AQAQ | 20 (40 μL) | 200 μL |
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RNF44 Gene Summary
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. [provided by RefSeq, Jul 2008]
Gene Name: Ring Finger Protein 44
Chromosome: CHR5: 175953699 -175964421
Locus: 5q35.2
NXF3 Gene Summary
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear RNA Export Factor 3
Chromosome: CHRX: 102330749 -102348022
Locus: Xq22.1
Gene Diseases
The RNF44 NXF3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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