RNF41-MYO1C Fusion FISH Probe
The RNF41-MYO1C Fusion FISH Probe is used to confirm a fusion of the RNF41 and MYO1C genes. The fusion of the RNF41 and MYO1C genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNF41-MYO1C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-RERE | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-REOR | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-REGO | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-REGR | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-REAQ | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-ORRE | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-OROR | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-ORGO | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-GORE | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-GOOR | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-GOGO | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-GOGR | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-GRRE | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-GROR | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-GRGO | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-GRGR | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-AQRE | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-AQOR | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-AQGO | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-AQGR | 20 (40 μL) | 200 μL |
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| RNF41-MYO1C-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO1C Gene Summary
This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008]
Gene Name: Myosin IC
Chromosome: CHR17: 1367479 -1396001
Locus: 17p13.3
RNF41 Gene Summary
This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
Gene Name: Ring Finger Protein 41
Chromosome: CHR12: 56596287 -56615753
Locus: 12q13.3
Gene Diseases
The RNF41 MYO1C Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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