RNF215-GRIN2B Fusion FISH Probe
The RNF215-GRIN2B Fusion FISH Probe is used to confirm a fusion of the RNF215 and GRIN2B genes. The fusion of the RNF215 and GRIN2B genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNF215-GRIN2B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-RERE | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-REOR | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-REGO | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-REGR | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-REAQ | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-ORRE | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-OROR | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-ORGO | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-GORE | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-GOOR | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-GOGO | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-GOGR | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-GRRE | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-GROR | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-GRGO | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-GRGR | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-AQRE | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-AQOR | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-AQGO | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-AQGR | 20 (40 μL) | 200 μL |
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| RNF215-GRIN2B-20-AQAQ | 20 (40 μL) | 200 μL |
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GRIN2B Gene Summary
This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia. [provided by RefSeq, Aug 2017]
Gene Name: Glutamate Ionotropic Receptor NMDA Type Subunit 2B
Chromosome: CHR12: 13714409 -14133022
Locus: 12p13.1
RNF215 Gene Summary
The Ring Finger Protein 215 (RNF215) gene is located on chr22 :30774802-30783302 at 22q12.2.
Gene Name: Ring Finger Protein 215
Chromosome: CHR22: 30774802 -30783302
Locus: 22q12.2
Gene Diseases
The RNF215 GRIN2B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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