RNF213-IL22RA1 Fusion FISH Probe
The RNF213-IL22RA1 Fusion FISH Probe is used to confirm a fusion of the RNF213 and IL22RA1 genes. The fusion of the RNF213 and IL22RA1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNF213-IL22RA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-RERE | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-REOR | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-REGO | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-REGR | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-REAQ | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-ORRE | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-OROR | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-ORGO | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-GORE | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-GOOR | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-GOGO | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-GOGR | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-GRRE | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-GROR | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-GRGO | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-GRGR | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-AQRE | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-AQOR | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-AQGO | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-AQGR | 20 (40 μL) | 200 μL |
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| RNF213-IL22RA1-20-AQAQ | 20 (40 μL) | 200 μL |
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RNF213 Gene Summary
This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Gene Name: Ring Finger Protein 213
Chromosome: CHR17: 78234666 -78370086
Locus: 17q25.3
IL22RA1 Gene Summary
The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]
Gene Name: Interleukin 22 Receptor Subunit Alpha 1
Chromosome: CHR1: 24446260 -24469775
Locus: 1p36.11
Gene Diseases
The RNF213 IL22RA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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