RNF19A-PRSS3 Fusion FISH Probe
The RNF19A-PRSS3 Fusion FISH Probe is used to confirm a fusion of the RNF19A and PRSS3 genes. The fusion of the RNF19A and PRSS3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNF19A-PRSS3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-RERE | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-REOR | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-REGO | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-REGR | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-REAQ | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-ORRE | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-OROR | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-ORGO | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-GORE | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-GOOR | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-GOGO | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-GOGR | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-GRRE | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-GROR | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-GRGO | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-GRGR | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-AQRE | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-AQOR | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-AQGO | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-AQGR | 20 (40 μL) | 200 μL |
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| RNF19A-PRSS3-20-AQAQ | 20 (40 μL) | 200 μL |
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PRSS3 Gene Summary
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2010]
Gene Name: Protease, Serine 3
Chromosome: CHR9: 33750463 -33799229
Locus: 9p13.3
RNF19A Gene Summary
This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Ring Finger Protein 19A, RBR E3 Ubiquitin Protein Ligase
Chromosome: CHR8: 101269287 -101322327
Locus: 8q22.2
Gene Diseases
The RNF19A PRSS3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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