RNF185-SMTN Fusion FISH Probe
The RNF185-SMTN Fusion FISH Probe is used to confirm a fusion of the RNF185 and SMTN genes. The fusion of the RNF185 and SMTN genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNF185-SMTN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-RERE | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-REOR | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-REGO | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-REGR | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-REAQ | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-ORRE | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-OROR | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-ORGO | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-GORE | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-GOOR | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-GOGO | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-GOGR | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-GRRE | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-GROR | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-GRGO | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-GRGR | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-AQRE | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-AQOR | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-AQGO | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-AQGR | 20 (40 μL) | 200 μL |
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| RNF185-SMTN-20-AQAQ | 20 (40 μL) | 200 μL |
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SMTN Gene Summary
This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. This gene is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2011]
Gene Name: Smoothelin
Chromosome: CHR22: 31477281 -31500610
Locus: 22q12.2
RNF185 Gene Summary
The Ring Finger Protein 185 (RNF185) gene is located on chr22 :31556137-31603005 at 22q12.2.
Gene Name: Ring Finger Protein 185
Chromosome: CHR22: 31556137 -31603005
Locus: 22q12.2
Gene Diseases
The RNF185 SMTN Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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