RNF165-PHLPP1 Fusion FISH Probe
The RNF165-PHLPP1 Fusion FISH Probe is used to confirm a fusion of the RNF165 and PHLPP1 genes. The fusion of the RNF165 and PHLPP1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNF165-PHLPP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-RERE | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-REOR | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-REGO | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-REGR | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-REAQ | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-ORRE | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-OROR | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-ORGO | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-GORE | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-GOOR | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-GOGO | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-GOGR | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-GRRE | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-GROR | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-GRGO | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-GRGR | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-AQRE | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-AQOR | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-AQGO | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-AQGR | 20 (40 μL) | 200 μL |
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| RNF165-PHLPP1-20-AQAQ | 20 (40 μL) | 200 μL |
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PHLPP1 Gene Summary
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]
Gene Name: PH Domain And Leucine Rich Repeat Protein Phosphatase 1
Chromosome: CHR18: 60382671 -60647666
Locus: 18q21.33
RNF165 Gene Summary
Encoded in regions involved in pericentric inversions in patients with bipolar affective disorder. [provided by RefSeq, Jul 2008]
Gene Name: Ring Finger Protein 165
Chromosome: CHR18: 43914186 -44040783
Locus: 18q21.1
Gene Diseases
The RNF165 PHLPP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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