RNF121-VPS37C Fusion FISH Probe
The RNF121-VPS37C Fusion FISH Probe is used to confirm a fusion of the RNF121 and VPS37C genes. The fusion of the RNF121 and VPS37C genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNF121-VPS37C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-RERE | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-REOR | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-REGO | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-REGR | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-REAQ | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-ORRE | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-OROR | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-ORGO | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-GORE | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-GOOR | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-GOGO | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-GOGR | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-GRRE | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-GROR | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-GRGO | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-GRGR | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-AQRE | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-AQOR | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-AQGO | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-AQGR | 20 (40 μL) | 200 μL |
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| RNF121-VPS37C-20-AQAQ | 20 (40 μL) | 200 μL |
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VPS37C Gene Summary
VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008]
Gene Name: VPS37C, ESCRT-I Subunit
Chromosome: CHR11: 60897727 -60928916
Locus: 11q12.2
RNF121 Gene Summary
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Several alternatively spliced transcript variants have been noted for this gene, however, not all are likely to encode viable protein products. [provided by RefSeq, Sep 2008]
Gene Name: Ring Finger Protein 121
Chromosome: CHR11: 71639767 -71708643
Locus: 11q13.4
Gene Diseases
The RNF121 VPS37C Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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