RNF121-VASP Fusion FISH Probe
The RNF121-VASP Fusion FISH Probe is used to confirm a fusion of the RNF121 and VASP genes. The fusion of the RNF121 and VASP genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNF121-VASP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-RERE | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-REOR | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-REGO | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-REGR | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-REAQ | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-ORRE | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-OROR | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-ORGO | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-GORE | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-GOOR | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-GOGO | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-GOGR | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-GRRE | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-GROR | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-GRGO | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-GRGR | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-AQRE | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-AQOR | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-AQGO | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-AQGR | 20 (40 μL) | 200 μL |
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| RNF121-VASP-20-AQAQ | 20 (40 μL) | 200 μL |
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VASP Gene Summary
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008]
Gene Name: Vasodilator Stimulated Phosphoprotein
Chromosome: CHR19: 46010687 -46030240
Locus: 19q13.32
RNF121 Gene Summary
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Several alternatively spliced transcript variants have been noted for this gene, however, not all are likely to encode viable protein products. [provided by RefSeq, Sep 2008]
Gene Name: Ring Finger Protein 121
Chromosome: CHR11: 71639767 -71708643
Locus: 11q13.4
Gene Diseases
The RNF121 VASP Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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