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RNF10-FBXO21 Fusion FISH Probe

The RNF10-FBXO21 Fusion FISH Probe is used to confirm a fusion of the RNF10 and FBXO21 genes. The fusion of the RNF10 and FBXO21 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RNF10-FBXO21-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RNF10-FBXO21-20-RERE 20 (40 μL) 200 μL
RNF10-FBXO21-20-REOR 20 (40 μL) 200 μL
RNF10-FBXO21-20-REGO 20 (40 μL) 200 μL
RNF10-FBXO21-20-REGR 20 (40 μL) 200 μL
RNF10-FBXO21-20-REAQ 20 (40 μL) 200 μL
RNF10-FBXO21-20-ORRE 20 (40 μL) 200 μL
RNF10-FBXO21-20-OROR 20 (40 μL) 200 μL
RNF10-FBXO21-20-ORGO 20 (40 μL) 200 μL
RNF10-FBXO21-20-ORAQ 20 (40 μL) 200 μL
RNF10-FBXO21-20-GORE 20 (40 μL) 200 μL
RNF10-FBXO21-20-GOOR 20 (40 μL) 200 μL
RNF10-FBXO21-20-GOGO 20 (40 μL) 200 μL
RNF10-FBXO21-20-GOGR 20 (40 μL) 200 μL
RNF10-FBXO21-20-GOAQ 20 (40 μL) 200 μL
RNF10-FBXO21-20-GRRE 20 (40 μL) 200 μL
RNF10-FBXO21-20-GROR 20 (40 μL) 200 μL
RNF10-FBXO21-20-GRGO 20 (40 μL) 200 μL
RNF10-FBXO21-20-GRGR 20 (40 μL) 200 μL
RNF10-FBXO21-20-GRAQ 20 (40 μL) 200 μL
RNF10-FBXO21-20-AQRE 20 (40 μL) 200 μL
RNF10-FBXO21-20-AQOR 20 (40 μL) 200 μL
RNF10-FBXO21-20-AQGO 20 (40 μL) 200 μL
RNF10-FBXO21-20-AQGR 20 (40 μL) 200 μL
RNF10-FBXO21-20-AQAQ 20 (40 μL) 200 μL

RNF10 Gene Summary

The protein encoded by this gene contains a ring finger motif, which is known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. EST data suggests the existence of multiple alternatively spliced transcript variants, however, their full length nature is not known. [provided by RefSeq, Jul 2008]

Gene Name: Ring Finger Protein 10

Chromosome: CHR12: 120972131 -121015397

Locus: 12q24.31

FBXO21 Gene Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]

Gene Name: F-box Protein 21

Chromosome: CHR12: 117581584 -117628300

Locus: 12q24.22

Gene Diseases

The RNF10 FBXO21 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.