RMND1-TIAM2 Fusion FISH Probe
The RMND1-TIAM2 Fusion FISH Probe is used to confirm a fusion of the RMND1 and TIAM2 genes. The fusion of the RMND1 and TIAM2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RMND1-TIAM2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-RERE | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-REOR | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-REGO | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-REGR | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-REAQ | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-ORRE | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-OROR | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-ORGO | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-GORE | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-GOOR | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-GOGO | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-GOGR | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-GRRE | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-GROR | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-GRGO | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-GRGR | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-AQRE | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-AQOR | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-AQGO | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-AQGR | 20 (40 μL) | 200 μL |
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| RMND1-TIAM2-20-AQAQ | 20 (40 μL) | 200 μL |
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TIAM2 Gene Summary
This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: T-cell Lymphoma Invasion And Metastasis 2
Chromosome: CHR6: 155411422 -155578857
Locus: 6q25.2-q25.3
RMND1 Gene Summary
The protein encoded by this gene belongs to the evolutionary conserved sif2 family of proteins that share the DUF155 domain in common. This protein is thought to be localized in the mitochondria and involved in mitochondrial translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-11. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Name: Required For Meiotic Nuclear Division 1 Homolog
Chromosome: CHR6: 151725988 -151773316
Locus: 6q25.1
Gene Diseases
The RMND1 TIAM2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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