RIOK1-EYS Fusion FISH Probe
The RIOK1-EYS Fusion FISH Probe is used to confirm a fusion of the RIOK1 and EYS genes. The fusion of the RIOK1 and EYS genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma, and Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RIOK1-EYS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-RERE | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-REOR | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-REGO | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-REGR | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-REAQ | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-ORRE | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-OROR | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-ORGO | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-ORAQ | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-GORE | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-GOOR | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-GOGO | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-GOGR | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-GOAQ | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-GRRE | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-GROR | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-GRGO | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-GRGR | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-GRAQ | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-AQRE | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-AQOR | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-AQGO | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-AQGR | 20 (40 μL) | 200 μL |
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| RIOK1-EYS-20-AQAQ | 20 (40 μL) | 200 μL |
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RIOK1 Gene Summary
The protein encoded by this gene competes with pICln for inclusion in the protein arginine methyltransferase 5 complex. This complex targets substrates for dimethylation. The encoded protein is essential for the last steps in the maturation of 40S subunits. [provided by RefSeq, Jan 2017]
Gene Name: RIO Kinase 1
Chromosome: CHR6: 7390061 -7418270
Locus: 6p24.3
EYS Gene Summary
The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: Eyes Shut Homolog (Drosophila)
Chromosome: CHR6: 64429875 -66417118
Locus: 6q12
Gene Diseases
The RIOK1 EYS Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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