RIF1-TNFAIP6 Fusion FISH Probe
The RIF1-TNFAIP6 Fusion FISH Probe is used to confirm a fusion of the RIF1 and TNFAIP6 genes. The fusion of the RIF1 and TNFAIP6 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RIF1-TNFAIP6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-RERE | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-REOR | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-REGO | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-REGR | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-REAQ | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-ORRE | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-OROR | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-ORGO | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-ORAQ | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-GORE | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-GOOR | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-GOGO | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-GOGR | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-GOAQ | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-GRRE | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-GROR | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-GRGO | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-GRGR | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-GRAQ | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-AQRE | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-AQOR | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-AQGO | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-AQGR | 20 (40 μL) | 200 μL |
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| RIF1-TNFAIP6-20-AQAQ | 20 (40 μL) | 200 μL |
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TNFAIP6 Gene Summary
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq, Dec 2010]
Gene Name: TNF Alpha Induced Protein 6
Chromosome: CHR2: 152214105 -152236562
Locus: 2q23.3
RIF1 Gene Summary
This gene encodes a protein that shares homology with the yeast teleomere binding protein, Rap1 interacting factor 1. This protein localizes to aberrant telomeres may be involved in DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
Gene Name: Replication Timing Regulatory Factor 1
Chromosome: CHR2: 152266396 -152333860
Locus: 2q23.3
Gene Diseases
The RIF1 TNFAIP6 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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