RICTOR-ISL1 Fusion FISH Probe
The RICTOR-ISL1 Fusion FISH Probe is used to confirm a fusion of the RICTOR and ISL1 genes. The fusion of the RICTOR and ISL1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RICTOR-ISL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-RERE | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-REOR | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-REGO | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-REGR | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-REAQ | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-ORRE | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-OROR | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-ORGO | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-GORE | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-GOOR | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-GOGO | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-GOGR | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-GRRE | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-GROR | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-GRGO | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-GRGR | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-AQRE | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-AQOR | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-AQGO | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-AQGR | 20 (40 μL) | 200 μL |
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| RICTOR-ISL1-20-AQAQ | 20 (40 μL) | 200 μL |
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ISL1 Gene Summary
This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]
Gene Name: ISL LIM Homeobox 1
Chromosome: CHR5: 50678957 -50690563
Locus: 5q11.1
RICTOR Gene Summary
RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008]
Gene Name: RPTOR Independent Companion Of MTOR Complex 2
Chromosome: CHR5: 38938021 -39074501
Locus: 5p13.1
Gene Diseases
The RICTOR ISL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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