RIC8B-ORAI1 Fusion FISH Probe
The RIC8B-ORAI1 Fusion FISH Probe is used to confirm a fusion of the RIC8B and ORAI1 genes. The fusion of the RIC8B and ORAI1 genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RIC8B-ORAI1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-RERE | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-REOR | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-REGO | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-REGR | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-REAQ | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-ORRE | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-OROR | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-ORGO | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-GORE | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-GOOR | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-GOGO | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-GOGR | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-GRRE | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-GROR | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-GRGO | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-GRGR | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-AQRE | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-AQOR | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-AQGO | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-AQGR | 20 (40 μL) | 200 μL |
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| RIC8B-ORAI1-20-AQAQ | 20 (40 μL) | 200 μL |
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RIC8B Gene Summary
The RIC8 Guanine Nucleotide Exchange Factor B (RIC8B) gene is located on chr12 :107168398-107283094 at 12q23.3.
Gene Name: RIC8 Guanine Nucleotide Exchange Factor B
Chromosome: CHR12: 107168398 -107283094
Locus: 12q23.3
ORAI1 Gene Summary
The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011]
Gene Name: ORAI Calcium Release-activated Calcium Modulator 1
Chromosome: CHR12: 122064454 -122079946
Locus: 12q24.31
Gene Diseases
The RIC8B ORAI1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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