RHPN2-GRIN2D Fusion FISH Probe
The RHPN2-GRIN2D Fusion FISH Probe is used to confirm a fusion of the RHPN2 and GRIN2D genes. The fusion of the RHPN2 and GRIN2D genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RHPN2-GRIN2D-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-RERE | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-REOR | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-REGO | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-REGR | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-REAQ | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-ORRE | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-OROR | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-ORGO | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-ORAQ | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-GORE | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-GOOR | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-GOGO | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-GOGR | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-GOAQ | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-GRRE | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-GROR | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-GRGO | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-GRGR | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-GRAQ | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-AQRE | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-AQOR | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-AQGO | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-AQGR | 20 (40 μL) | 200 μL |
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| RHPN2-GRIN2D-20-AQAQ | 20 (40 μL) | 200 μL |
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GRIN2D Gene Summary
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]
Gene Name: Glutamate Ionotropic Receptor NMDA Type Subunit 2D
Chromosome: CHR19: 48898131 -48948188
Locus: 19q13.33
RHPN2 Gene Summary
This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009]
Gene Name: Rhophilin Rho GTPase Binding Protein 2
Chromosome: CHR19: 33469497 -33555824
Locus: 19q13.11
Gene Diseases
The RHPN2 GRIN2D Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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