RHOT2-DPEP1 Fusion FISH Probe
The RHOT2-DPEP1 Fusion FISH Probe is used to confirm a fusion of the RHOT2 and DPEP1 genes. The fusion of the RHOT2 and DPEP1 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RHOT2-DPEP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-RERE | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-REOR | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-REGO | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-REGR | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-REAQ | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-ORRE | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-OROR | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-ORGO | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-GORE | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-GOOR | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-GOGO | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-GOGR | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-GRRE | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-GROR | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-GRGO | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-GRGR | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-AQRE | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-AQOR | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-AQGO | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-AQGR | 20 (40 μL) | 200 μL |
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| RHOT2-DPEP1-20-AQAQ | 20 (40 μL) | 200 μL |
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DPEP1 Gene Summary
The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Dipeptidase 1
Chromosome: CHR16: 89679715 -89704839
Locus: 16q24.3
RHOT2 Gene Summary
This gene encodes a member of the Rho family of GTPases. The encoded protein is localized to the outer mitochondrial membrane and plays a role in mitochondrial trafficking and fusion-fission dynamics. [provided by RefSeq, Nov 2011]
Gene Name: Ras Homolog Family Member T2
Chromosome: CHR16: 718132 -724171
Locus: 16p13.3
Gene Diseases
The RHOT2 DPEP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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