RHOBTB1-ATP6V1C2 Fusion FISH Probe
The RHOBTB1-ATP6V1C2 Fusion FISH Probe is used to confirm a fusion of the RHOBTB1 and ATP6V1C2 genes. The fusion of the RHOBTB1 and ATP6V1C2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RHOBTB1-ATP6V1C2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-RERE | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-REOR | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-REGO | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-REGR | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-REAQ | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-ORRE | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-OROR | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-ORGO | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-GORE | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-GOOR | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-GOGO | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-GOGR | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-GRRE | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-GROR | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-GRGO | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-GRGR | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-AQRE | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-AQOR | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-AQGO | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-AQGR | 20 (40 μL) | 200 μL |
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| RHOBTB1-ATP6V1C2-20-AQAQ | 20 (40 μL) | 200 μL |
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RHOBTB1 Gene Summary
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Gene Name: Rho Related BTB Domain Containing 1
Chromosome: CHR10: 62629197 -62761198
Locus: 10q21.2
ATP6V1C2 Gene Summary
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008]
Gene Name: ATPase H+ Transporting V1 Subunit C2
Chromosome: CHR2: 10861774 -10925236
Gene Diseases
The RHOBTB1 ATP6V1C2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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