RGS3-ABCA1 Fusion FISH Probe
The RGS3-ABCA1 Fusion FISH Probe is used to confirm a fusion of the RGS3 and ABCA1 genes. The fusion of the RGS3 and ABCA1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RGS3-ABCA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-RERE | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-REOR | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-REGO | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-REGR | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-REAQ | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-ORRE | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-OROR | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-ORGO | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-GORE | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-GOOR | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-GOGO | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-GOGR | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-GRRE | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-GROR | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-GRGO | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-GRGR | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-AQRE | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-AQOR | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-AQGO | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-AQGR | 20 (40 μL) | 200 μL |
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| RGS3-ABCA1-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCA1 Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily A Member 1
Chromosome: CHR9: 107543283 -107690527
Locus: 9q31.1
RGS3 Gene Summary
This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plasma membrane-associated with a function in Wnt signaling and in the epithelial mesenchymal transition, while shorter N-terminally-truncated isoforms can be nuclear. [provided by RefSeq, Jan 2013]
Gene Name: Regulator Of G Protein Signaling 3
Chromosome: CHR9: 116207010 -116360018
Locus: 9q32
Gene Diseases
The RGS3 ABCA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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