RGS12-PDZRN3 Fusion FISH Probe
The RGS12-PDZRN3 Fusion FISH Probe is used to confirm a fusion of the RGS12 and PDZRN3 genes. The fusion of the RGS12 and PDZRN3 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RGS12-PDZRN3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-RERE | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-REOR | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-REGO | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-REGR | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-REAQ | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-ORRE | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-OROR | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-ORGO | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-ORAQ | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-GORE | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-GOOR | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-GOGO | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-GOGR | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-GOAQ | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-GRRE | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-GROR | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-GRGO | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-GRGR | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-GRAQ | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-AQRE | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-AQOR | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-AQGO | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-AQGR | 20 (40 μL) | 200 μL |
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| RGS12-PDZRN3-20-AQAQ | 20 (40 μL) | 200 μL |
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RGS12 Gene Summary
This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Regulator Of G Protein Signaling 12
Chromosome: CHR4: 3315873 -3441640
Locus: 4p16.3
PDZRN3 Gene Summary
This gene encodes a member of the LNX (Ligand of Numb Protein-X) family of RING-type ubiquitin E3 ligases. This protein may function in vascular morphogenesis and the differentiation of adipocytes, osteoblasts and myoblasts. This protein may be targeted for degradation by the human papilloma virus E6 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: PDZ Domain Containing Ring Finger 3
Chromosome: CHR3: 73431651 -73674072
Locus: 3p13
Gene Diseases
The RGS12 PDZRN3 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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