RGL2-DAXX Fusion FISH Probe
The RGL2-DAXX Fusion FISH Probe is used to confirm a fusion of the RGL2 and DAXX genes. The fusion of the RGL2 and DAXX genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RGL2-DAXX-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-RERE | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-REOR | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-REGO | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-REGR | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-REAQ | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-ORRE | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-OROR | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-ORGO | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-ORAQ | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-GORE | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-GOOR | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-GOGO | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-GOGR | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-GOAQ | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-GRRE | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-GROR | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-GRGO | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-GRGR | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-GRAQ | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-AQRE | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-AQOR | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-AQGO | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-AQGR | 20 (40 μL) | 200 μL |
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| RGL2-DAXX-20-AQAQ | 20 (40 μL) | 200 μL |
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DAXX Gene Summary
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
Gene Name: Death Domain Associated Protein
Chromosome: CHR6_cox_hap2: 4730148 -4734611
Locus: 6p21.32
RGL2 Gene Summary
The Ral Guanine Nucleotide Dissociation Stimulator Like 2 (RGL2) gene is located on chr6_mcf_hap5 :4733174-4740909 at 6p21.32.
Gene Name: Ral Guanine Nucleotide Dissociation Stimulator Like 2
Chromosome: CHR6_mcf_hap5: 4733174 -4740909
Locus: 6p21.32
Gene Diseases
The RGL2 DAXX Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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