RFX3-SMARCA2 Fusion FISH Probe
The RFX3-SMARCA2 Fusion FISH Probe is used to confirm a fusion of the RFX3 and SMARCA2 genes. The fusion of the RFX3 and SMARCA2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RFX3-SMARCA2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-RERE | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-REOR | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-REGO | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-REGR | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-REAQ | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-ORRE | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-OROR | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-ORGO | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-GORE | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-GOOR | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-GOGO | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-GOGR | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-GRRE | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-GROR | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-GRGO | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-GRGR | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-AQRE | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-AQOR | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-AQGO | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-AQGR | 20 (40 μL) | 200 μL |
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| RFX3-SMARCA2-20-AQAQ | 20 (40 μL) | 200 μL |
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RFX3 Gene Summary
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]
Gene Name: Regulatory Factor X3
Chromosome: CHR9: 3224646 -3525983
Locus: 9p24.2
SMARCA2 Gene Summary
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014]
Gene Name: SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 2
Chromosome: CHR9: 2015341 -2193623
Locus: 9p24.3
Gene Diseases
The RFX3 SMARCA2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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