RFX3-DDAH2 Fusion FISH Probe
The RFX3-DDAH2 Fusion FISH Probe is used to confirm a fusion of the RFX3 and DDAH2 genes. The fusion of the RFX3 and DDAH2 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RFX3-DDAH2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-RERE | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-REOR | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-REGO | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-REGR | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-REAQ | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-ORRE | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-OROR | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-ORGO | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-GORE | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-GOOR | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-GOGO | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-GOGR | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-GRRE | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-GROR | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-GRGO | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-GRGR | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-AQRE | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-AQOR | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-AQGO | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-AQGR | 20 (40 μL) | 200 μL |
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| RFX3-DDAH2-20-AQAQ | 20 (40 μL) | 200 μL |
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RFX3 Gene Summary
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]
Gene Name: Regulatory Factor X3
Chromosome: CHR9: 3224646 -3525983
Locus: 9p24.2
DDAH2 Gene Summary
This gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: Dimethylarginine Dimethylaminohydrolase 2
Chromosome: CHR6_qbl_hap6: 2988446 -2991669
Locus: 6p21.33
Gene Diseases
The RFX3 DDAH2 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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