RFX3-ARID4B Fusion FISH Probe
The RFX3-ARID4B Fusion FISH Probe is used to confirm a fusion of the RFX3 and ARID4B genes. The fusion of the RFX3 and ARID4B genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RFX3-ARID4B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-RERE | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-REOR | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-REGO | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-REGR | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-REAQ | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-ORRE | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-OROR | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-ORGO | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-ORAQ | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-GORE | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-GOOR | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-GOGO | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-GOGR | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-GOAQ | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-GRRE | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-GROR | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-GRGO | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-GRGR | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-GRAQ | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-AQRE | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-AQOR | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-AQGO | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-AQGR | 20 (40 μL) | 200 μL |
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| RFX3-ARID4B-20-AQAQ | 20 (40 μL) | 200 μL |
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RFX3 Gene Summary
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]
Gene Name: Regulatory Factor X3
Chromosome: CHR9: 3224646 -3525983
Locus: 9p24.2
ARID4B Gene Summary
This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: AT-rich Interaction Domain 4B
Chromosome: CHR1: 235330209 -235491532
Locus: 1q42.3
Gene Diseases
The RFX3 ARID4B Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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