RFWD2-GRM1 Fusion FISH Probe
The RFWD2-GRM1 Fusion FISH Probe is used to confirm a fusion of the RFWD2 and GRM1 genes. The fusion of the RFWD2 and GRM1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RFWD2-GRM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-RERE | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-REOR | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-REGO | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-REGR | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-REAQ | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-ORRE | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-OROR | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-ORGO | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-GORE | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-GOOR | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-GOGO | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-GOGR | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-GRRE | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-GROR | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-GRGO | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-GRGR | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-AQRE | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-AQOR | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-AQGO | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-AQGR | 20 (40 μL) | 200 μL |
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| RFWD2-GRM1-20-AQAQ | 20 (40 μL) | 200 μL |
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GRM1 Gene Summary
This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Gene Name: Glutamate Metabotropic Receptor 1
Chromosome: CHR6: 146348781 -146758731
Locus: 6q24.3
RFWD2 Gene Summary
The Ring Finger And WD Repeat Domain 2 (RFWD2) gene is located on chr1 :175913966-176176370 at 1q25.1-q25.2.
Gene Name: Ring Finger And WD Repeat Domain 2
Chromosome: CHR1: 175913966 -176176370
Locus: 1q25.1-q25.2
Gene Diseases
The RFWD2 GRM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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