RFTN1-DAZL Fusion FISH Probe
The RFTN1-DAZL Fusion FISH Probe is used to confirm a fusion of the RFTN1 and DAZL genes. The fusion of the RFTN1 and DAZL genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RFTN1-DAZL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-RERE | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-REOR | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-REGO | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-REGR | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-REAQ | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-ORRE | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-OROR | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-ORGO | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-ORAQ | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-GORE | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-GOOR | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-GOGO | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-GOGR | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-GOAQ | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-GRRE | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-GROR | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-GRGO | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-GRGR | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-GRAQ | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-AQRE | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-AQOR | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-AQGO | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-AQGR | 20 (40 μL) | 200 μL |
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| RFTN1-DAZL-20-AQAQ | 20 (40 μL) | 200 μL |
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DAZL Gene Summary
The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Name: Deleted In Azoospermia Like
Chromosome: CHR3: 16628300 -16647006
Locus: 3p24.3
RFTN1 Gene Summary
The Raftlin, Lipid Raft Linker 1 (RFTN1) gene is located on chr3 :16357351-16555222 at 3p24.3.
Gene Name: Raftlin, Lipid Raft Linker 1
Chromosome: CHR3: 16357351 -16555222
Locus: 3p24.3
Gene Diseases
The RFTN1 DAZL Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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