REV3L-FN3KRP Fusion FISH Probe
The REV3L-FN3KRP Fusion FISH Probe is used to confirm a fusion of the REV3L and FN3KRP genes. The fusion of the REV3L and FN3KRP genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| REV3L-FN3KRP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-RERE | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-REOR | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-REGO | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-REGR | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-REAQ | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-ORRE | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-OROR | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-ORGO | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-ORAQ | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-GORE | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-GOOR | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-GOGO | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-GOGR | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-GOAQ | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-GRRE | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-GROR | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-GRGO | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-GRGR | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-GRAQ | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-AQRE | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-AQOR | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-AQGO | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-AQGR | 20 (40 μL) | 200 μL |
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| REV3L-FN3KRP-20-AQAQ | 20 (40 μL) | 200 μL |
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REV3L Gene Summary
The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of Mobius syndrome. [provided by RefSeq, Jan 2017]
Gene Name: REV3 Like, DNA Directed Polymerase Zeta Catalytic Subunit
Chromosome: CHR6: 111620233 -111804414
Locus: 6q21
FN3KRP Gene Summary
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
Gene Name: Fructosamine 3 Kinase Related Protein
Chromosome: CHR17: 80674581 -80685893
Locus: 17q25.3
Gene Diseases
The REV3L FN3KRP Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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