RER1-DDX21 Fusion FISH Probe
The RER1-DDX21 Fusion FISH Probe is used to confirm a fusion of the RER1 and DDX21 genes. The fusion of the RER1 and DDX21 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RER1-DDX21-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-RERE | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-REOR | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-REGO | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-REGR | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-REAQ | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-ORRE | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-OROR | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-ORGO | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-ORAQ | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-GORE | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-GOOR | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-GOGO | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-GOGR | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-GOAQ | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-GRRE | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-GROR | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-GRGO | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-GRGR | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-GRAQ | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-AQRE | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-AQOR | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-AQGO | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-AQGR | 20 (40 μL) | 200 μL |
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| RER1-DDX21-20-AQAQ | 20 (40 μL) | 200 μL |
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DDX21 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]
Gene Name: DExD-box Helicase 21
Chromosome: CHR10: 70715891 -70744279
Locus: 10q22.1
RER1 Gene Summary
The protein encoded by this gene is a multi-pass membrane protein that is localized to the golgi apparatus. It is involved in the retention of endoplasmic reticulum (ER) membrane proteins in the ER and retrieval of ER membrane proteins from the early Golgi compartment to facilitate gamma-secretase complex assembly. [provided by RefSeq, Oct 2009]
Gene Name: Retention In Endoplasmic Reticulum Sorting Receptor 1
Chromosome: CHR1: 2323213 -2336885
Locus: 1p36.32
Gene Diseases
The RER1 DDX21 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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