REPS2-APOO Fusion FISH Probe
The REPS2-APOO Fusion FISH Probe is used to confirm a fusion of the REPS2 and APOO genes. The fusion of the REPS2 and APOO genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| REPS2-APOO-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-RERE | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-REOR | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-REGO | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-REGR | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-REAQ | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-ORRE | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-OROR | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-ORGO | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-ORAQ | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-GORE | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-GOOR | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-GOGO | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-GOGR | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-GOAQ | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-GRRE | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-GROR | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-GRGO | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-GRGR | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-GRAQ | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-AQRE | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-AQOR | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-AQGO | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-AQGR | 20 (40 μL) | 200 μL |
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| REPS2-APOO-20-AQAQ | 20 (40 μL) | 200 μL |
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REPS2 Gene Summary
The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: RALBP1 Associated Eps Domain Containing 2
Chromosome: CHRX: 16964813 -17171403
Locus: Xp22.2
APOO Gene Summary
This gene is a member of the apolipoprotein family. Members of this protein family are involved in the transport and metabolism of lipids. The encoded protein associates with HDL, LDL and VLDL lipoproteins and is characterized by chondroitin-sulfate glycosylation. This protein may be involved in preventing lipid accumulation in the myocardium in obese and diabetic patients. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 4, 5, 12 and 16.[provided by RefSeq, Sep 2009]
Gene Name: Apolipoprotein O
Chromosome: CHRX: 23851464 -23926057
Locus: Xp22.11
Gene Diseases
The REPS2 APOO Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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