RCOR1-PPP2R5C Fusion FISH Probe
The RCOR1-PPP2R5C Fusion FISH Probe is used to confirm a fusion of the RCOR1 and PPP2R5C genes. The fusion of the RCOR1 and PPP2R5C genes has been associated with Ovarian Serous Cystadenocarcinoma, and Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RCOR1-PPP2R5C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-RERE | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-REOR | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-REGO | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-REGR | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-REAQ | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-ORRE | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-OROR | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-ORGO | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-ORAQ | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-GORE | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-GOOR | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-GOGO | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-GOGR | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-GOAQ | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-GRRE | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-GROR | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-GRGO | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-GRGR | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-GRAQ | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-AQRE | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-AQOR | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-AQGO | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-AQGR | 20 (40 μL) | 200 μL |
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| RCOR1-PPP2R5C-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP2R5C Gene Summary
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Protein Phosphatase 2 Regulatory Subunit B'gamma
Chromosome: CHR14: 102228134 -102394328
Locus: 14q32.31
RCOR1 Gene Summary
This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor). [provided by RefSeq, Aug 2011]
Gene Name: REST Corepressor 1
Chromosome: CHR14: 103058995 -103196913
Locus: 14q32.31-q32.32
Gene Diseases
The RCOR1 PPP2R5C Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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