RBM6-IDH2 Fusion FISH Probe
The RBM6-IDH2 Fusion FISH Probe is used to confirm a fusion of the RBM6 and IDH2 genes. The fusion of the RBM6 and IDH2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RBM6-IDH2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-RERE | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-REOR | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-REGO | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-REGR | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-REAQ | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-ORRE | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-OROR | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-ORGO | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-GORE | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-GOOR | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-GOGO | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-GOGR | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-GRRE | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-GROR | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-GRGO | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-GRGR | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-AQRE | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-AQOR | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-AQGO | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-AQGR | 20 (40 μL) | 200 μL |
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| RBM6-IDH2-20-AQAQ | 20 (40 μL) | 200 μL |
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IDH2 Gene Summary
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Gene Name: Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial
Chromosome: CHR15: 90627211 -90645708
Locus: 15q26.1
RBM6 Gene Summary
The RNA Binding Motif Protein 6 (RBM6) gene is located on chr3 :49977476-50114685 at 3p21.31.
Gene Name: RNA Binding Motif Protein 6
Chromosome: CHR3: 49977476 -50114685
Locus: 3p21.31
Gene Diseases
The RBM6 IDH2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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