RB1CC1-MMP16 Fusion FISH Probe
The RB1CC1-MMP16 Fusion FISH Probe is used to confirm a fusion of the RB1CC1 and MMP16 genes. The fusion of the RB1CC1 and MMP16 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RB1CC1-MMP16-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-RERE | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-REOR | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-REGO | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-REGR | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-REAQ | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-ORRE | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-OROR | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-ORGO | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-ORAQ | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-GORE | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-GOOR | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-GOGO | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-GOGR | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-GOAQ | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-GRRE | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-GROR | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-GRGO | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-GRGR | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-GRAQ | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-AQRE | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-AQOR | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-AQGO | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-AQGR | 20 (40 μL) | 200 μL |
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| RB1CC1-MMP16-20-AQAQ | 20 (40 μL) | 200 μL |
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MMP16 Gene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq, Oct 2010]
Gene Name: Matrix Metallopeptidase 16
Chromosome: CHR8: 89049459 -89339717
Locus: 8q21.3
RB1CC1 Gene Summary
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]
Gene Name: RB1 Inducible Coiled-coil 1
Chromosome: CHR8: 53535017 -53627026
Locus: 8q11.23
Gene Diseases
The RB1CC1 MMP16 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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