RB1-CNIH3 Fusion FISH Probe
The RB1-CNIH3 Fusion FISH Probe is used to confirm a fusion of the RB1 and CNIH3 genes. The fusion of the RB1 and CNIH3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RB1-CNIH3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-RERE | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-REOR | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-REGO | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-REGR | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-REAQ | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-ORRE | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-OROR | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-ORGO | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-ORAQ | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-GORE | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-GOOR | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-GOGO | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-GOGR | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-GOAQ | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-GRRE | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-GROR | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-GRGO | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-GRGR | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-GRAQ | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-AQRE | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-AQOR | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-AQGO | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-AQGR | 20 (40 μL) | 200 μL |
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| RB1-CNIH3-20-AQAQ | 20 (40 μL) | 200 μL |
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RB1 Gene Summary
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
Gene Name: RB Transcriptional Corepressor 1
Chromosome: CHR13: 48877882 -49056026
Locus: 13q14.2
CNIH3 Gene Summary
The Cornichon Family AMPA Receptor Auxiliary Protein 3 (CNIH3) gene is located on chr1 :224804178-224928249 at 1q42.12.
Gene Name: Cornichon Family AMPA Receptor Auxiliary Protein 3
Chromosome: CHR1: 224804178 -224928249
Locus: 1q42.12
Gene Diseases
The RB1 CNIH3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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