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RAVER1-TYK2 Fusion FISH Probe

The RAVER1-TYK2 Fusion FISH Probe is used to confirm a fusion of the RAVER1 and TYK2 genes. The fusion of the RAVER1 and TYK2 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RAVER1-TYK2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RAVER1-TYK2-20-RERE 20 (40 μL) 200 μL
RAVER1-TYK2-20-REOR 20 (40 μL) 200 μL
RAVER1-TYK2-20-REGO 20 (40 μL) 200 μL
RAVER1-TYK2-20-REGR 20 (40 μL) 200 μL
RAVER1-TYK2-20-REAQ 20 (40 μL) 200 μL
RAVER1-TYK2-20-ORRE 20 (40 μL) 200 μL
RAVER1-TYK2-20-OROR 20 (40 μL) 200 μL
RAVER1-TYK2-20-ORGO 20 (40 μL) 200 μL
RAVER1-TYK2-20-ORAQ 20 (40 μL) 200 μL
RAVER1-TYK2-20-GORE 20 (40 μL) 200 μL
RAVER1-TYK2-20-GOOR 20 (40 μL) 200 μL
RAVER1-TYK2-20-GOGO 20 (40 μL) 200 μL
RAVER1-TYK2-20-GOGR 20 (40 μL) 200 μL
RAVER1-TYK2-20-GOAQ 20 (40 μL) 200 μL
RAVER1-TYK2-20-GRRE 20 (40 μL) 200 μL
RAVER1-TYK2-20-GROR 20 (40 μL) 200 μL
RAVER1-TYK2-20-GRGO 20 (40 μL) 200 μL
RAVER1-TYK2-20-GRGR 20 (40 μL) 200 μL
RAVER1-TYK2-20-GRAQ 20 (40 μL) 200 μL
RAVER1-TYK2-20-AQRE 20 (40 μL) 200 μL
RAVER1-TYK2-20-AQOR 20 (40 μL) 200 μL
RAVER1-TYK2-20-AQGO 20 (40 μL) 200 μL
RAVER1-TYK2-20-AQGR 20 (40 μL) 200 μL
RAVER1-TYK2-20-AQAQ 20 (40 μL) 200 μL

TYK2 Gene Summary

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]

Gene Name: Tyrosine Kinase 2

Chromosome: CHR19: 10461203 -10491248

Locus: 19p13.2

RAVER1 Gene Summary

The Ribonucleoprotein, PTB Binding 1 (RAVER1) gene is located on chr19 :10426888-10444314 at 19p13.2.

Gene Name: Ribonucleoprotein, PTB Binding 1

Chromosome: CHR19: 10426888 -10444314

Locus: 19p13.2

Gene Diseases

The RAVER1 TYK2 Fusion has been associated with the following diseases:

Disease Name
Adrenocortical Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.